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The therapeutic ingredients of Di Bella’s multi-therapy (MDB) include somatostatine, octreotide, retinoids, Vitamins E, D, C,
melatonin, bromocriptine, micro-doses of anti-blastic drugs (at dose levels 100-200 times lower than chemotherapy).
Differently from cytotoxic and cytolytic chemotherapy, the mechanism of action of MDB treatment is a pro-apoptopic one.
The absolute majority of the 34,508 published reports on such ingredients – available as of Dec. 22, 2002 on MedLine - National Library
of Medicine, and on this website under the section entitled ”MDB-Active Ingredients” – describe MDB effectiveness in countering the key
features of cancer biology from onset to progression, that is: high proliferative rate, lack of cell differentiation, hence failure of
apoptosis i.e. the main natural anti-blastic mechanism. These features are common to all cancer types
Even in prevention MDB has proved to be effective in respect of major factors of tumor etiopathogenesis, like oxidant agents and free
radicals. MDB components like retinoids and other vitamins that help protect the epithelium, like vitamins E and D, are especially
recommended in treating epithelial tumors. These vitamins, besides powerfully improving trophicity, integrity and functional recovery
of epithelia, strongly limit - together with melatonin - cytotoxic damage caused by ionizing radiations of radiotherapy to neighboring
epithelial tissues, as well as oxidative and free radical damage on nuclear DNA, cytosolic organelles and cell membranes.
MDB is therefore an effective, causal solution to cancer, while chemotherapy does not act upon the cause, but rather on the product
of the cancerous process, i.e. the tumor cells. Chemotherapy deludingly aims at destroying all tumor cell populations: in fact some
of these cells mutate and adjust, becoming more and more drug resistant, and rapidly proliferate in an increasingly weaker body whose
anti-blastic, homeostatic and immune mechanisms have been severely, often irreversibly, compromised by chemotherapy.
By countering the manifold and changing etiopathogenic chains of cancerogenesis, MDB treatment helps redress the biological and
physiological balance, the upsetting of which allowed the onset of cancer – even in the presence of solid tumors, cancer should
always be considered as a systemic disease, with cancerous mass being only the maximum evidenced concentration. With MDB treatment,
notably the interaction and synergy of its components, cancer biology reverts to physiological biology. While every single molecule
exerts an anti-blastic action, their synergy powerfully improves MDB anti-tumor effectiveness. Somatostatine, bromocriptine and
melatonin inhibit both pituitary hormones - like GH, prolactin, powerful and ubiquitous growth factors whose role in cancerogenesis
is well documented - and IGF1, TGF, EGF, VEGF, PDGF, NGF, gastrin, FGF, colecistokinin – major factors in cancer etiopathogenesis.
The Di Bella method stems from the need to remedy the substantial inability of chemotherapy to cure cancer, as much is evidenced by the
employment of oncological surgery, which would be pointless if chemotherapy were really effective.